Tools of Genetic Research Molecular Biology
نویسنده
چکیده
Re c e n t a dva n c e s in m o l e c u l a r b io l og y t ech n i q u e s p er m i t scientists to identify genetic contributions to alcoholism. Two main types of technology are commonly used to identify genes that cause or predispose a person to a disease: positional cloning techniques and candidate gene techniques. Positional cloning techniques allow disease genes to be identified based solel y o n t hei r loc a t ion w i th in t h e genom e wi t h o ut p rior knowledge of the gene’s function. Techniques for confirming t h e r o l e o f c a n d i d a t e g e n e s r e l y o n s u f f i c i e n t p r i o r understanding of the disease process to implicate possible diseaserelated genes. Scientists use cloning techniques or the application of certain enzymes to reproduce a candidate gene in sufficient quantity for study. As the human genome project progresses and the gene map becomes increasingly complete, more and more disease genes will be identified through a combination of positional cloning and the candidate gene ap p r oac h. KE Y W O R D S : A O D d ep e n d e n c e ; g e ne ; r e s e ar c h ; l a b o r a t o r y m e t h o d ; m o l e c u l a r g e n e t i c s ; g e n o m e ; g e n e t i c mapping; genetic linkage; environmental factors; etiology
منابع مشابه
Using two retrotransposon-based marker systems (SRAP and REMAP) for genetic diversity analysis of Moroccan Argan tree
The Argania is an endemic genetic resource in Morocco holding an important ecological and socio-economical benefit. However, overgrazing and overharvesting lead to a serious downturn in the number of trees. To characterize genetic diversity within and among 24 populations, represented by 240 argan trees, four combinations of SRAP primers and eight combinations of REMAP primers were used. A tota...
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Acipenser stellatus (stellate sturgeon) that has been intensively captured for decades represents a sturgeon species of great importance for the scientific community and fishermen. Besides overfishing and poaching, their reproduction sites have been destroyed and their natural habitats were affected by pollution. In consequence, wild populations of stellate sturgeon have decreased dramatically ...
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Genetic Variation Among Salvia Species Based on Sequence-Related Amplified Polymorphism (SRAP) Marker
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The importance of grain cultivation especially wheat is obvious in terms of providing human and animal food and its impact on the economy of human societies. The reduction of genetic diversity in cultivars prevents increasing yields in line with rising demand and consumption. Therefore, it is necessary to improve the compatibility of them and increase their genetic extent. In the current, the g...
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تاریخ انتشار 2014